tocolytic agents การใช้

There is no need for chronic administration of tocolytic agents since postoperative uterine contractions are barely ever observed.
Indometacin is an effective tocolytic agent, able to delay premature labor by reducing uterine contractions through inhibition of prostaglandin synthesis in the uterus and possibly through calcium channel blockade.
While the use of tocolytic agents or the development of preeclampsia ( toxemia of pregnancy ) and pregnancy-induced hypertension ( PIH ) may contribute to the worsening of heart failure, they do not cause PPCM; the majority of women have developed PPCM who neither received tocolytics nor had preeclampsia nor PIH.